Absence of VEGFR‐1/Flt‐1 signaling pathway in mice results in insensitivity to discogenic low back pain in an established disc injury mouse model

Author:

Qiu Sujun1ORCID,Shi Changgui2,Anbazhagan Arivarasu Natarajan3,Das Vaskar4,Arora Vipin5,Kc Ranjan6,Li Xin7,O‐Sullivan InSug3,Wijnen Andre8ORCID,Chintharlapalli Sudhakar9,Gott‐Velis Gina710,Richard Ripper10,Mwale Fackson1112,Shibuya Masabumi13,Min Shaoxiong1,Im Hee‐Jeong714

Affiliation:

1. Department of Spinal Surgery, Zhujiang HospitalSouthern Medical University Guangzhou China

2. Department of Orthopedic Surgery, Changzheng HospitalThe Second Military Medical University of China Shanghai China

3. Department of MedicineUniversity of Illinois at Chicago Chicago Illinois

4. Department of AnesthesiologyRush University Medical Center Chicago Illinois

5. Department of Anesthesia, Critical Care and Pain MedicineMassachusetts General Hospital Boston Massachusetts

6. Division of Orthopedic SurgeryThe Children's Hospital of Philadelphia Research Institute Philadelphia Pennsylvania

7. Department of BioengineeringUniversity of Illinois at Chicago Chicago Illinois

8. Department of Orthopedic SurgeryMayo Clinic Rochester Minnesota

9. Department of Immuno‐oncology, Lilly Research LaboratoriesEli Lilly and Company Indianapolis Indiana

10. Departments of AnesthesiologyUniversity of Illinois at Chicago Chicago Illinois

11. Orthopaedics Research Laboratory, Lady Davis Institute for Medical ResearchSMBD‐Jewish General Hospital Montreal Quebec Canada

12. Department of Experimental Surgery, Faculty of MedicineMcGill University Montreal Quebec Canada

13. Division of Genetics, Institute of Physiology and MedicineJobu University Takasaki Japan

14. Research & Development DepartmentJesse Brown Veterans Affairs Medical Center at Chicago Chicago Illinois

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

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