Organocatalytic Enantioselective Syntheses of Flavonoids and Cannabinoids-Reference-Cited by-同舟云学术

Organocatalytic Enantioselective Syntheses of Flavonoids and Cannabinoids

Published:2023-11-28 Issue: Volume: Page:
ISSN:1615-4150
Container-title:Advanced Synthesis & Catalysis
language:en
Short-container-title:Adv Synth Catal

Author:

Vidal‐Albalat Andreu¹,Matos Paz Bruno²^ORCID

Affiliation:

1. Departamento de Farmacia Universidad Cardenal Herrera-CEU, CEU Universities C/Ramón y Cajal s/n 46115 Alfara del Patriarca Valencia Spain

2. Department of Fundamental Chemistry Institute of Chemistry University of São Paulo Avenida Professor Lineu Prestes, 748 05508-000 São Paulo Brazil

Abstract

AbstractFlavonoids and cannabinoids comprise two large families of natural products that contain a chromane moiety in their structure. Their therapeutic potential has been extensively investigated as potential treatments to several diseases, ranging from cancer to infectious and neurodegenerative diseases. Despite their relative structural simplicity, in recent years creative synthetic methodologies were designed to overcome limitations from the previous synthetic strategies applied to these compounds. The aim of this review is to provide a comprehensive overview of all the enantioselective organocatalytic strategies that have been applied to the synthesis of flavonoids and cannabinoids to date.

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adsc.202301168

Reference75 articles.

1. Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis

2. Antibacterial activity and mechanism of plant flavonoids to gram-positive bacteria predicted from their lipophilicities

3. Antiviral activities of flavonoids

4. Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms