Affiliation:
1. Center for Molecular Imaging and Nuclear Medicine State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University Suzhou 215123 China
2. Department of Radiology The First Affiliated Hospital of Soochow University Soochow University Suzhou 215000 China
Abstract
Selective internal radiation therapy (SIRT) as one of the radiotherapeutic techniques has been widely used in the treatment of primary and metastatic liver cancer, for better avoiding radiation damage to normal tissues from external exposure. The radioactive microspheres used in SIRT should meet some special requirements closely associated with the type of radionuclides and the size and the property of the microsphere. This review focuses on the radioactive microspheres to elaborate the current challenges in the related fields, including simplification of the preparation of microspheres formed by different materials, visualization of the biodistribution of microspheres, and the suitability of different types of microspheres for repeated treatment. In this context, the major characteristics of three kinds of commercialized radioactive microspheres are compared, the advances in the radioactive microspheres achieved in recent years are summarized, and the future prospects of radioactive microspheres are discussed.
Funder
National Natural Science Foundation of China
National Key Research and Development Program of China
Priority Academic Program Development of Jiangsu Higher Education Institutions
Cited by
1 articles.
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