Affiliation:
1. Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA
2. Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA
3. Department of Neurology Alzheimer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands
4. Faculty of Behavioral and Movement Sciences Clinical Developmental Psychology and Clinical Neuropsychology Vrije Universiteit Amsterdam Amsterdam The Netherlands
5. RAND Corporation Boston Massachusetts USA
Abstract
AbstractINTRODUCTIONTo investigate the utility of a new digital tool for measuring everyday functioning in preclinical Alzheimer's disease, we piloted the Assessment of Smartphone Everyday Tasks (ASSET) application.METHODSForty‐six participants (50.3 ± 27.1 years; 67% female; 20 young unimpaired, 17 old unimpaired, 9 mildly cognitively impaired) completed ASSET 7 times. ASSET comprises two main tasks, simulating a Patient Portal and a Calendar. We assessed ASSET's internal consistency, test–retest reliability, and user experience.RESULTSASSET main tasks correlated with each other (r = 0.75, 95% confidence interval [CI] = [0.58, 0.86]). Performance on ASSET's Patient Portal related to cognition (r = 0.64, 95% CI = [0.42, 0.79]) and observer ratings of everyday functioning (r = 0.57, 95% CI = [0.24, 0.79]). Test–retest reliability was good (intraclass correlation coefficient = 0.87, 95% CI = [0.77, 0.93]). Most participants rated their experience with ASSET neutrally or positively.DISCUSSIONASSET is a promising smartphone‐based digital assessment of everyday functioning. Future studies may investigate its utility for early diagnosis and evaluation of treatment of Alzheimer's disease.
Subject
Psychiatry and Mental health,Neurology (clinical)