Effect of Futibatinib on Cardiac Repolarization: Results of a Randomized, Controlled, Double‐Blind, QT/QTc, Phase 1 Study in Healthy Subjects
Author:
Affiliation:
1. Taiho Oncology, Inc. Princeton New Jersey USA
2. Celerion Tempe Arizona USA
3. Sonnichsen Pharmaceutical Associates LLC Collegeville Pennsylvania USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.1195
Reference26 articles.
1. Futibatinib Is a Novel Irreversible FGFR 1–4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors
2. Phase I, first-in-human study of futibatinib, a highly selective, irreversible FGFR1–4 inhibitor in patients with advanced solid tumors
3. Futibatinib, an Irreversible FGFR1–4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF/FGFR Aberrations: A Phase I Dose-Expansion Study
4. GoyalL Meric‐BernstamF HollebecqueA et al.Primary results of FOENIX‐CCA2: the irreversible FGFR1–4 inhibitor futibatinib in intrahepatic cholangiocarcinoma (iCCA) with FGFR2 fusions/rearrangements [abstract]. In:Proceedings of the 112th Annual Meeting of the American Association for Cancer Research; April 10–15 2021;Philadelphia PA. Abstract CT010. Accessed June 1 2022.
5. A phase III study of futibatinib (TAS‐120) versus gemcitabine‐cisplatin (gem‐cis) chemotherapy as first‐line (1L) treatment for patients (pts) with advanced (adv) cholangiocarcinoma (CCA) harboring fibroblast growth factor receptor 2 (FGFR2) gene rearrangements (FOENIX‐CCA3);Borad MJ;J Clin Oncol,2020
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