PGE1and E3show lower efficacies than E2to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors-Reference-Cited by-同舟云学术

PGE1and E3show lower efficacies than E2to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors

Published:2017-11 Issue:22 Volume:591 Page:3771-3780
ISSN:0014-5793
Container-title:FEBS Letters
language:en
Short-container-title:FEBS Lett

Author:

Araki Yumi¹²,Suganami Akiko³,Endo Suzu¹,Masuda Yuta¹,Fukushima Keijo¹,Regan John W.⁴,Murayama Toshihiko²,Tamura Yutaka³,Fujino Hiromichi¹

Affiliation:

1. Department of Molecular Pharmacology; Graduate School of Pharmaceutical Sciences and Graduate School of Biomedical Sciences; Tokushima University; Japan

2. Laboratory of Chemical Pharmacology; Graduate School of Pharmaceutical Sciences; Chiba University; Japan

3. Department of Bioinformatics; Graduate School of Medicine; Chiba University; Japan

4. Department of Pharmacology and Toxicology; College of Pharmacy; The University of Arizona; Tucson AZ USA

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics

Reference24 articles.

1. Prostaglandin EP receptors: targets for treatment and prevention of colorectal cancer?;Hull;Mol Cancer Res,2004

2. The role of cyclooxygenase-2 and prostaglandin in colon cancer;Eisinger;Prostaglandins Other Lipid Mediat,2007

3. Cancer prevention: a new era beyond cyclooxygenase-2;Rigas;J Pharmacol Exp Ther,2005

4. International union of basic and clinical pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress;Woodward;Pharmacol Rev,2011

5. The prostanoid EP4 receptor and its signaling pathway;Yokoyama;Pharmacol Rev,2013

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. EP4 Receptor Conformation Sensor Suited for Ligand Screening and Imaging of Extracellular Prostaglandins;Molecular Pharmacology;2023-07-13

2. The Biased Activities of Prostanoids and Their Receptors: Review and Beyond;Biological and Pharmaceutical Bulletin;2022-06-01

3. The Gαs‐protein‐mediated pathway may be steadily stimulated by prostanoid EP2 receptors, but not by EP4 receptors;FEBS Open Bio;2022-02-15

4. Why PGD 2 has different functions from PGE 2;BioEssays;2020-11-09

5. Network pharmacology combined with metabolomics approach to investigate the protective role and detoxification mechanism of Yunnan Baiyao formulation;Phytomedicine;2020-10