Nirmatrelvir–ritonavir for the treatment of COVID‐19 patients: A systematic review and meta‐analysis

Author:

Cheema Huzaifa A.1,Jafar Uzair1ORCID,Sohail Aruba2,Shahid Abia1,Sahra Syeda3,Ehsan Muhammad1,Athar Farwa1,Shah Jaffer4,Sah Ranjit5

Affiliation:

1. Division of Infectious Diseases, Department of Medicine King Edward Medical University Lahore Pakistan

2. Department of Medicine Dow University of Health Sciences Karachi Pakistan

3. Department of Infectious Diseases University of Oklahoma Health Sciences Center Oklahoma City Oklahoma USA

4. New York State Department of Health Albany New York USA

5. Tribhuvan University Teaching Hospital Institute of Medicine Kathmandu Nepal

Publisher

Wiley

Subject

Infectious Diseases,Virology

Reference19 articles.

1. Efficacy and safety of molnupiravir for COVID-19 patients

2. U.S. Food and Drug Administration (FDA). Coronavirus (COVID‐19) Update: FDA Authorizes First Oral Antiviral for Treatment of COVID‐19. Food and Drug Administration. Published 2021. Accessed October 18 2022.https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-oral-antiviral-treatment-covid-19

3. Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with confirmed SARS-CoV-2 infection during the omicron wave in Hong Kong: an observational study

4. Real‐world effectiveness of nirmatrelvir/ritonavir in preventing hospitalization among patients with COVID‐19 at high risk for severe disease in the United States: a nationwide population‐based cohort study;Zhou X;medRxiv,2022

5. Oral Nirmatrelvir and Ritonavir in Nonhospitalized Vaccinated Patients With Coronavirus Disease 2019

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1. Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity;ACS Pharmacology & Translational Science;2024-01-19

2. Nirmatrelvir/ritonavir for COVID-19: an overview of systematic reviews;Journal of Antimicrobial Chemotherapy;2023-12-12

3. Nirmatrelvir combined with ritonavir for preventing and treating COVID-19;Cochrane Database of Systematic Reviews;2023-11-30

4. COVID-19 Treatments: Then and Now;The Journal of Allergy and Clinical Immunology: In Practice;2023-11

5. Nirmatrelvir/ritonavir use in patients with COVID-19 on hemodialysis: a case series;Diagnostic Microbiology and Infectious Disease;2023-11

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