Tremor in Pediatric Populations: Clinical Characteristics, Differential Diagnosis, and Management Challenges

Author:

Ghadery Christine M1,Gorodetsky Carolina2ORCID,Lang Anthony E1ORCID

Affiliation:

1. Department of Medicine, Edmond J. Safra Program in Parkinson's Disease University Health Network and the Division of Neurology; University of Toronto Toronto Ontario Canada

2. Department of Pediatrics, Division of Neurology The Hospital for Sick Children; University of Toronto Toronto Ontario Canada

Abstract

AbstractBackgroundTremor is a hyperkinetic movement disorder defined as a rhythmic, involuntary, oscillatory movement of a body part. It can present as early as in the neonatal period and may be an isolated finding or part of an associated neurological or systemic disorder. Although it is commonly seen in childhood, it is not frequently described in the literature.ObjectivesThis review aims to provide a clinically useful overview of pediatric tremors based on the current literature.MethodsWe identified relevant studies published in English by searching PubMed (until February 2024), using the following subject headings: pediatric/tremor, deep brain stimulation, and focused ultrasound.ResultsData from 65 articles were critically reviewed with focus on tremor classification, etiologies, clinical features, and management.ConclusionSome tremor disorders in children can persist into adulthood, however, others are exclusively seen in the pediatric population. The lack of epidemiological and clinical studies in the pediatric population creates substantial challenges for pediatricians, and medical decisions are mostly guided by adult data.

Publisher

Wiley

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