Development of oral extended release formulations of 6-hydroxybuspirone

Author:

Nicholson Sarah J.1,Timmins Peter1,Dockens Randy C.2,Connor Alyson3,Croop Robert4,Ferrie Peter1,Zeng Jianing5,Dennis Andrew B.1,Wilding Ian3

Affiliation:

1. Drug Product Science and Technology, Research and Development; Bristol-Myers Squibb; Moreton; Merseyside; CH46 1QW; UK

2. Discovery Medicine and Clinical Pharmacology, Research and Development; Bristol-Myers Squibb; Princeton; NJ; 08543; USA

3. Quotient Clinical; Ruddington; Nottingham; NG11 6JS; UK

4. Global Clinical Research, Research and Development; Bristol-Myers Squibb; Princeton; NJ; 08543; USA

5. Analytical and Bioanalytical Development, Research and Development; Bristol-Myers Squibb; Princeton; NJ; 08543; USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference39 articles.

1. Pharmacokinetics and disposition of 13C-buspirone HCl after intravenous and oral dosing in man;Mayol;Clin Pharmacol Ther,1985

2. Metabolism and disposition of buspirone;Gammans;Am J Med,1986

3. Metabolism of the antianxiety drug buspirone in human subjects;Jaloo;Drug Metab Dispos,1989

4. Pharmacokinetics of a newly identified active metabolite of buspirone after administration of buspirone over its therapeutic dose range;Dockens;J Clin Pharmacol,2006

5. 1-(2-Pyrimidinyl)-piperazine as active metabolite of buspirone in man and rat;Caccia;Pharmacology,1986

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