An apolipoprotein E mimetic peptide with activities against multidrug-resistant bacteria and immunomodulatory effects

Author:

Wang Chuan-qing1,Yang Chang-sheng2,Yang Yi3,Pan Fu1,He Lei-yan1,Wang Ai-min1

Affiliation:

1. The Clinical Microbiology Lab, Department of Nosocomial Infection Control; Children's Hospital of Fudan University; 399 Wanyuan Road Shanghai 201102 China

2. Department of Cardiology; Zhongshan Hospital of Fudan University, Shanghai Institute of Cardiovascular Diseases; 180 Fenglin Road Shanghai 200032 China

3. The Institute of Pediatrics, Key Laboratory of Neonatal Diseases; Ministry of Public Health, Children's Hospital of Fudan University; 399 Wanyuan Road Shanghai 201102 China

Funder

Shanghai Municipal Natural Science Foundation

Publisher

Wiley

Subject

Organic Chemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry,Structural Biology

Reference34 articles.

1. Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections;Nijnik;Emerg Health Threats J,2009

2. Defensins: antimicrobial peptides of innate immunity;Ganz;Nat. Rev. Immunol.,2003

3. Antimicrobial peptides of multicellular organisms;Zasloff;Nature,2002

4. Roles of antimicrobial peptides such as defensins in innate and adaptive immunity;Oppenheim;Ann. Rheum. Dis.,2003

5. Apolipoprotein e: cholesterol transport protein with expanding role in cell biology;Mahley;Science,1988

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