Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A-Reference-Cited by-同舟云学术

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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A

Published:2016-01-08 Issue:8 Volume:11 Page:893-899
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Patrone James D.¹²,Pelz Nicholas F.¹,Bates Brittney S.¹,Souza-Fagundes Elaine M.¹,Vangamudi Bhavatarini¹,Camper Demarco V.¹,Kuznetsov Alexey G.¹,Browning Carrie F.¹,Feldkamp Michael D.¹,Frank Andreas O.¹,Gilston Benjamin A.¹,Olejniczak Edward T.¹,Rossanese Olivia W.¹,Waterson Alex G.³⁴,Chazin Walter J.¹⁴,Fesik Stephen W.¹³⁴

Affiliation:

1. Department of Biochemistry; Vanderbilt University; Nashville TN 37232 USA

2. Department of Chemistry; Rollins College; 1000 Holt Avenue Winter Park FL 32789 USA

3. Department of Pharmacology; Vanderbilt University; Nashville TN 37232 USA

4. Department of Chemistry; Vanderbilt University; Nashville TN 37232 USA

Funder

Vanderbilt High-Throughput Screening Core

US National Institutes of Health (NIH)

American Recovery and Reinvestment Act (ARRA)

National Council for Scientific and Technological Development (CNPq)

Federal University of Minas Gerais (Brazil)

Deutscher Akademischer Austauschdienst (DAAD)

NIH National Research Service Award (NRSA)

NIH NRSA

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201500479/fullpdf

Reference25 articles.

1. REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

2. Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

3. The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling

4. A dynamic model for replication protein A (RPA) function in DNA processing pathways

5. ATR and ATRIP: Partners in Checkpoint Signaling

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1. The Intriguing Mystery of RPA Phosphorylation in DNA Double-Strand Break Repair;Genes;2024-01-27

2. Synthesis, Molecular Docking, and Biological Evaluation of Novel Anthranilic Acid Hybrid and Its Diamides as Antispasmodics;International Journal of Molecular Sciences;2023-09-08

3. Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1;Nature Communications;2023-07-20

4. CSAlign and CSAlign-Dock: Structure alignment of ligands considering full flexibility and application to protein–ligand docking;Computational and Structural Biotechnology Journal;2023

5. Medicinal chemistry of anthranilic acid derivatives: A mini review;Drug Development Research;2021-06-12

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