Rational Development of Novel Activity Probes for the Analysis of Human Cytochromes P450-Reference-Cited by-同舟云学术

Rational Development of Novel Activity Probes for the Analysis of Human Cytochromes P450

Published:2016-05-06 Issue:11 Volume:11 Page:1122-1128
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Sellars Jonathan D.¹^ORCID,Skipsey Mark¹,Sadr-ul-Shaheed ²,Gravell Sebastian²,Abumansour Hamza²,Kashtl Ghasaq²,Irfan Jawaria²,Khot Mohamed²,Pors Klaus²,Patterson Laurence H.²,Sutton Chris W.²

Affiliation:

1. School of Medicine, Pharmacy and Health; Durham University; Queen's Campus; University Boulevard Stockton-on-Tees TS17 6BH UK

2. The Institute of Cancer Therapeutics; University of Bradford; West Yorkshire BD7 1DP UK

Funder

Engineering and Physical Sciences Research Council (EPSRC)

Yorkshire Cancer Research

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference41 articles.

1. Substrate binding to cytochromes P450

2. P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations

3. Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

4. Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes

5. Colon Cancer–Specific Cytochrome P450 2W1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins

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4. Probing cytochrome P450 bioactivation and fluorescent properties with morpholinyl-tethered anthraquinones;Bioorganic & Medicinal Chemistry Letters;2018-05

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