The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain

Author:

Gattlen Christophe12,Deftu Alexandru‐Florian123,Tonello Raquel4,Ling Yuejuan45,Berta Temugin4,Ristoiu Violeta3,Suter Marc René126ORCID

Affiliation:

1. Pain Center, Department of AnesthesiologyLausanne University Hospital and University of Lausanne (CHUV) Lausanne Switzerland

2. Faculty of Biology and Medicine (FBM)University of Lausanne (UNIL) Lausanne Switzerland

3. Department of Anatomy, Animal Physiology and Biophysics, Faculty of BiologyUniversity of Bucharest Bucharest Romania

4. Pain Research Center, Department of AnesthesiologyUniversity of Cincinnati Medical Center Cincinnati Ohio USA

5. Pain Research LaboratoryInstitute of Nautical Medicine, Jiangsu Key Laboratory of Neurodegeneration, University of Nantong Nantong Jiangsu China

6. Department of Fundamental Neurosciences, Faculty of Biology and Medicine (FBM)University of Lausanne (UNIL) Lausanne Switzerland

Funder

Foundation for the National Institutes of Health

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

SCIEX

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

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