Affiliation:
1. Leibniz Institute for Solid State and Materials Research (IFW Dresden) 01069 Dresden Germany
2. Department of Chemistry Faculty of Science University of Maroua P.O. Box 814 Maroua Cameroon
Abstract
AbstractA polycationic organohalloysite (H‐polyQ22) prepared by the sequential grafting of methylamine and 1,4‐butanediol diglycidyl ether in the interlayer space of (3‐aminopropyl)trimethoxysilane grafted halloysite is herein employed as a carbon paste electrode (CPE) modifier for the electrochemical determination of mangiferin, a bioactive molecule. When H‐polyQ22 was used as CPE modifier, the cyclic voltammetric response of mangiferin increased by ca. 8‐fold. This electrochemical response enhancement was shown to be the result of the great preconcentration capacity of H‐polyQ22. Since the H‐polyQ22 modified CPE proved to be a good signal enhancer, a new methodology for the sensitive determination of mangiferin was developed using square wave voltammetry. Under optimised conditions, a linear correlation between peak current and mangiferin concentration was obtained in the range from 0 to 2775.67 nM. A detection limit of 5.47×10−10 M was obtained based on a signal to noise ratio of 3, with a sensitivity of 193.58 μA/μM. The ability of some possible interferents such as human serum albumin, L‐cystine, ascorbic acid, glucose, dopamine and phenol to perturb the electrochemical signal of mangiferin in real sample analysis was alsoinvestigated.
Funder
Alexander von Humboldt-Stiftung
Subject
Electrochemistry,Analytical Chemistry