Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation-Reference-Cited by-同舟云学术

Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation

Published:2019-04-02 Issue:11 Volume:234 Page:19121-19129
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Prudovsky Igor¹^ORCID,Carter Damien¹²,Kacer Doreen¹,Palmeri Monica¹³,Soul Tee¹,Kumpel Chloe¹,Pyburn Kathleen¹,Barrett Karyn¹,DeMambro Victoria¹,Alexandrov Ilya⁴,Brandina Irina⁴,Kramer Robert¹³,Rappold Joseph¹²³

Affiliation:

1. Maine Medical Center Research Institute, Maine Medical Center Scarborough Maine

2. Maine Medical Center Department of Trauma, Maine Medical Center Portland Maine

3. Maine Medical Center Cardiovascular Institute, Maine Medical Center Portland Maine

4. ActivSignal Company Natick Massachusetts

Funder

American Association for the Surgery of Trauma

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.28603

Reference35 articles.

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3. Tranexamic acid suppresses the release of mitochondrial DAMPs and reduces lung inflammation in a murine burn model

4. A Rational Approach to Perioperative Fluid Management

5. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

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