Affiliation:
1. Department of Mechanical and Product Design Engineering Swinburne University of Technology Melbourne Australia
2. ENOVIS Lewisville Texas USA
Abstract
AbstractThe use of light for therapeutic applications requires light‐absorption by cellular chromophores at the target tissues and the subsequent photobiomodulation (PBM) of cellular biochemical processes. For transdermal deep tissue light therapy (tDTLT) to be clinically effective, a sufficiently large number of photons must reach and be absorbed at the targeted deep tissue sites. Thus, delivering safe and effective tDTLT requires understanding the physics of light propagation in tissue. This study simulates laser light propagation in an anatomically accurate human knee model to assess the light transmittance and light absorption‐driven thermal changes for eight commonly used laser therapy wavelengths (600–1200 nm) at multiple skin‐applied irradiances (W cm−2) with continuous wave (CW) exposures. It shows that of the simulated parameters, 2.38 W cm−2 (30 W, 20 mm beam radius) of 1064 nm light generated the least tissue heating −4°C at skin surface, after 30 s of CW irradiation, and the highest overall transmission—approximately 3%, to the innermost muscle tissue.
Subject
General Physics and Astronomy,General Engineering,General Biochemistry, Genetics and Molecular Biology,General Materials Science,General Chemistry