Practical and Selective sp 3 C−H Bond Chlorination via Aminium Radicals
Author:
Affiliation:
1. Department of Chemistry University of Manchester Oxford Road Manchester M13 9PL UK
2. Dipartimento di Scienze e Tecnologie Chimiche Università “Tor Vergata” Via della Ricerca Scientifica 00133 Rome Italy
Funder
Engineering and Physical Sciences Research Council
European Research Council
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202100030
Reference106 articles.
1. Chlorinated Hydrocarbons
2. Halogen-Mediated Conversion of Hydrocarbons to Commodities
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4. Cross-Coupling Reaction of Alkyl Halides with Grignard Reagents Catalyzed by Ni, Pd, or Cu Complexes with π-Carbon Ligand(s)
5. A Method for Palladium-Catalyzed Cross-Couplings of Simple Alkyl Chlorides: Suzuki Reactions Catalyzed by [Pd2(dba)3]/PCy3 dba=(E,E)-dibenzylideneacetone, Cy=cyclohexyl. We thank Dr. Matthew R. Netherton for helpful discussions and Johnson Matthey Inc. for supplying palladium compounds. Support has been provided by the Deutsche Akademie der Naturforscher Leopoldina (Leopoldina fellowship to J.H.K., BMBF-LPD 9901/8-48), Bristol-Myers Squibb, the National Institutes of Health (National Institute of General Medical Sciences, R01-GM62871), the Natural Sciences and Engineering Research Council of Canada (postdoctoral fellowship to C.D.), and Novartis. Funding for the MIT Department of Chemistry Instrumentation Facility has been provided in part by NSF CHE-9808061 and NSF DBI-9729592.
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