Identification of absorbed constituents and metabolites in rat plasma after oral administration of Shen-Song-Yang-Xin using ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry

Author:

Shi Tao12,Yao Zhihong12,Qin Zifei12,Ding Bo12,Dai Yi12,Yao Xinsheng123

Affiliation:

1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy; Jinan University; Guangzhou 510632 People's Republic of China

2. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research; Jinan University; Guangzhou 510632 People's Republic of China

3. School of Traditional Materia Medica; Shenyang Pharmaceutical University; Shenyang 110016 People's Republic of China

Funder

National Major Scientific and Technological Special Project of China

National Program on Key Basic Research Project of China

Program of Introducing Talents of Discipline to Universities

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference50 articles.

1. Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MSn;Dai;Journal of Pharmaceutical and Biomedical Analysis,2008

2. Mechanistic studies on the antidiabetic activity of a polysaccharide-rich extract of radix Ophiopogonis;Ding;Phytotherapy Research,2012

3. The effects of Shensongyangxin capsule in treating patients with angina pectoris;Fu;Chinese Journal of Difficult and Complicated Cases,2006

4. Effect of Shensong Yangxin capsule on ventricular premature beat and cardiovascular autonomic nervous function in patients with coronary heart disease;Gu;Chinese Journal of Integrated Traditional and Western Medicine,2005

5. Characterization of Triterpenic Acids in Fruits of Ziziphus Species by HPLC-ELSD-MS;Guo;Journal of Agricultural and Food Chemistry,2010

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