Production of afucosylated antibodies in CHO cells by coexpression of an anti‐FUT8 intrabody-Reference-Cited by-同舟云学术

Production of afucosylated antibodies in CHO cells by coexpression of an anti‐FUT8 intrabody

Published:2022-05-14 Issue:8 Volume:119 Page:2206-2220
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotech & Bioengineering

Author:

Joubert Simon¹,Guimond Julie¹,Perret Sylvie¹,Malenfant Félix¹,Elahi S. Mehdy¹,Marcil Anne¹,Parat Marie¹,Gilbert Michel²,Lenferink Anne E.G.¹,Baardsnes Jason¹,Durocher Yves¹

Affiliation:

1. Human Health Therapeutics Research Center, National Research Council Canada Montréal Quebec Canada

2. Human Health Therapeutics Research Center, National Research Council Canada Ottawa Ontario Canada

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.28127

Reference47 articles.

1. Rapid cGMP manufacturing of COVID‐19 monoclonal antibody using stable CHO cell pools

2. Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase

3. Nonselective and Efficient Fluorescent Labeling of Glycans Using 2-Amino Benzamide and Anthranilic Acid

4. Impact of N-glycosylation on Fcγ receptor / IgG interactions: unravelling differences with an enhanced surface plasmon resonance biosensor assay based on coiled-coil interactions

5. Small-molecule control of antibody N-glycosylation in engineered mammalian cells

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