A nationwide analysis of salvage surgery for laryngeal cancer in the elderly

Author:

Raad Richard A.1ORCID,Holland Katie1,Ritz Ethan M.2,Tajudeen Bobby A.1,Al‐Khudari Samer1,Stenson Kerstin1,Teitcher Joshua3,Fidler Mary Jo3,Jelinek Michael3ORCID,Joshi Nikhil4,Bhayani Mihir K.1

Affiliation:

1. Department of Otorhinolaryngology—Head & Neck Surgery Rush University Medical Center Chicago Illinois USA

2. Rush University Bioinformatics and Biostatistics Core Rush University Chicago Illinois USA

3. Department of Internal Medicine, Division of Hematology Oncology and Cell Therapy, Rush University Medical Center Chicago Illinois USA

4. Department of Radiation Oncology Rush University Medical Center Chicago Illinois USA

Abstract

AbstractBackgroundWe aim to describe outcomes of elderly patients undergoing salvage surgery for laryngeal cancer and to characterize the interplay of age with various other factors in this growing population.MethodsUsing the National Cancer Database, we identified cases of salvage laryngectomy in patients who failed chemoradiation. An age cutoff of 70 years was used to separate subjects into two groups. Various factors were compared.ResultsOf the 825 patients included, 166 (20.1%) were elderly. Elderly patients had worse overall survival (p = 0.001), higher 30‐day and 90‐day mortality (p = 0.006, p < 0.001), and a longer length of stay (LOS) (p = 0.015). LOS over 1 week was associated with worse survival (p = 0.032).ConclusionElderly patients had worse overall perioperative survival than their younger counterparts. LOS and 30‐day readmissions were associated with higher risk of mortality in this group. We provide a contemporary set of relevant information for head and neck cancer providers to consider in this growing population

Publisher

Wiley

Subject

Otorhinolaryngology

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