Radiomics in colorectal cancer

Author:

Wu Long1ORCID,Wu Huan2ORCID,Li Chen3,Zhang Baofang2,Li Xiaoyun1,Zhen Yunhuan1,Li Haiyang4ORCID

Affiliation:

1. Department of Anus and Intestinal Surgery The Affiliated Hospital of Guizhou Medical University Guiyang Guizhou China

2. Department of Infectious Diseases The Affiliated Hospital of Guizhou Medical University Guiyang Guizhou China

3. Department of Biology, Chemistry, Pharmacy Free University of Berlin Berlin Germany

4. Department of Hepatobiliary Surgery The Affiliated Hospital of Guizhou Medical University Guiyang Guizhou China

Abstract

AbstractColorectal cancer (CRC) is a global health challenge with high morbidity and mortality. Radiomics, an emerging field, utilizes quantitative imaging features extracted from medical images for CRC diagnosis, staging, treatment response assessment, and prognostication. This review highlights the potential of radiomics for personalized CRC management. Radiomics enables noninvasive tumor characterization, aiding in early detection and accurate diagnosis, and it can be used to predict tumor stage, lymph node involvement, and prognosis. Furthermore, radiomics guides personalized therapies by assessing the treatment response and identifying patients who could benefit. Challenges include standardizing imaging protocols and analysis techniques. Robust validation frameworks and user‐friendly software are needed for the integration of radiomics into clinical practice. Despite challenges, radiomics offers valuable insights into tumor biology, treatment response, and prognosis in CRC. Overcoming technical and clinical hurdles will unlock its full potential in CRC management.

Funder

National Natural Science Foundation of China

Publisher

Wiley

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