Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians

Author:

Ping Jie1,Yang Yaohua1,Wen Wanqing1,Kweon Sun‐Seog2,Matsuda Koichi3,Jia Wei‐Hua4ORCID,Shin Aesun56ORCID,Gao Yu‐Tang7,Matsuo Keitaro89ORCID,Kim Jeongseon10ORCID,Kim Dong‐Hyun11,Jee Sun Ha12,Cai Qiuyin1,Chen Zhishan1,Tao Ran13,Shin Min‐Ho2,Tanikawa Chizu14,Pan Zhi‐Zhong4,Oh Jae Hwan15,Oze Isao16ORCID,Ahn Yoon‐Ok5,Jung Keum Ji12,Ren Zefang17ORCID,Shu Xiao‐Ou1ORCID,Long Jirong1,Zheng Wei1ORCID

Affiliation:

1. Division of Epidemiology, Department of Medicine, Vanderbilt‐Ingram Cancer Center, Vanderbilt Epidemiology Center Vanderbilt University School of Medicine Nashville Tennessee USA

2. Department of Preventive Medicine Chonnam National University Medical School Gwangju South Korea

3. Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences University of Tokyo Tokyo Japan

4. State Key Laboratory of Oncology in South China, Cancer Center Sun Yat‐sen University Guangzhou China

5. Department of Preventive Medicine Seoul National University College of Medicine Seoul South Korea

6. Cancer Research Institute Seoul National University Seoul South Korea

7. State Key Laboratory of Oncogenes and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China

8. Division of Molecular and Clinical Epidemiology Aichi Cancer Center Research Institute Nagoya Japan

9. Department of Epidemiology Nagoya University Graduate School of Medicine Nagoya Japan

10. Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy National Cancer Center Gyeonggi‐do South Korea

11. Department of Social and Preventive Medicine Hallym University College of Medicine Okcheon‐dong South Korea

12. Department of Epidemiology and Health Promotion, Graduate School of Public Health Yonsei University Seoul South Korea

13. Department of Biostatistics Vanderbilt University Nashville Tennessee USA

14. Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science University of Tokyo Tokyo Japan

15. Center for Colorectal Cancer, National Cancer Center Hospital National Cancer Center Gyeonggi‐do South Korea

16. Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Nagoya Japan

17. School of Public Health Sun Yat‐sen University Guangzhou China

Funder

National Institutes of Health

National Cancer Center

National Natural Science Foundation of China

National Key Research and Development Program of China

Vanderbilt-Ingram Cancer Center

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference40 articles.

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