Complement C5a potentiates uric acid crystal-induced IL-1β production
Author:
Affiliation:
1. Department of Respiratory; Inflammation and Autoimmune Diseases, MedImmune, LLC; Gaithersburg MD USA
2. Department of Antibody Discovery and Protein Engineering; MedImmune, LLC; Gaithersburg MD USA
Funder
MedImmune, LLC
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201444560/fullpdf
Reference43 articles.
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3. Gout-associated uric acid crystals activate the NALP3 inflammasome;Martinon;Nature,2006
4. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals;Chen;J. Clin. Invest.,2006
5. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation;Rajamaki;PLoS One,2010
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