Mutation in <scp>MCL1</scp> predicted loop to helix structural transition stabilizes <scp>MCL1–Bax</scp> binding interaction favoring cancer cell survival-Reference-Cited by-同舟云学术

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Mutation in MCL1 predicted loop to helix structural transition stabilizes MCL1–Bax binding interaction favoring cancer cell survival

Published:2022-04-23 Issue:9 Volume:90 Page:1699-1713
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Deepak Shyl Eby‐nesar Stella‐glory¹^ORCID,Malgija Beutline²,Iniyan Appadurai Muthamil¹³^ORCID,Vincent Samuel Gnana Prakash¹^ORCID

Affiliation:

1. International Centre for Nanobiotechnology (ICN), Centre for Marine Science and Technology (CMST) Manonmaniam Sundaranar University Kanyakumari Tamil Nadu India

2. Computational Science Laboratory, MCC‐MRF Innovation Park Madras Christian College Chennai Tamil Nadu India

3. York Bioscience Private Limited Ambattur Industrial Estate Chennai Tamil Nadu India

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.26347

Reference50 articles.

1. BCL-2 family proteins: changing partners in the dance towards death

2. BH3-only proteins in cell death initiation, malignant disease and anticancer therapy

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