Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments-Reference-Cited by-同舟云学术

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments

Published:2020-11-09 Issue:4 Volume:22 Page:743-753
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Petri László¹,Ábrányi‐Balogh Péter¹,Tímea Imre²,Pálfy Gyula³,Perczel András³,Knez Damijan⁴,Hrast Martina⁴,Gobec Martina⁴,Sosič Izidor⁴,Nyíri Kinga⁵,Vértessy Beáta G.⁵⁶,Jänsch Niklas⁷,Desczyk Charlotte⁷,Meyer‐Almes Franz‐Josef⁷,Ogris Iza⁸,Golič Grdadolnik Simona⁸,Iacovino Luca Giacinto⁹,Binda Claudia⁹,Gobec Stanislav⁴^ORCID,Keserű György M.¹

Affiliation:

1. Medicinal Chemistry Research Group Research Centre for Natural Sciences Magyar tudósok krt 2 1117 Budapest Hungary

2. MS Metabolomics Research Group Research Centre for Natural Sciences Magyar tudósok krt 2 1117 Budapest Hungary

3. Laboratory of Structural Chemistry and Biology & MTA-ELTE Protein Modelling Research Group Eötvös Loránd University Pázmány Péter sétány 1/A 1117 Budapest Hungary

4. Faculty of Pharmacy University of Ljubljana Aškerčeva 7 1000 Ljubljana Slovenia

5. Genome Metabolism Research Group Research Centre for Natural Sciences Magyar tudósok krt 2 1117 Budapest Hungary

6. Department of Applied Biotechnology Budapest University of Technology and Economics Szt Gellért tér 4 1111 Budapest Hungary

7. Department of Chemical Engineering and Biotechnology University of Applied Sciences Darmstadt Schnittspahnstraße 12 64287 Darmstadt Germany

8. Laboratory for Molecular Structural Dynamics National Institute of Chemistry Hajdrihova 19 1000 Ljubljana Slovenia

9. Department of Biology and Biotechnology University of Pavia via Ferrata 1 27100 Pavia Italy

Funder

Javna Agencija za Raziskovalno Dejavnost RS

Ministry for Innovation and Technology

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202000700

Reference63 articles.

2. Targeted Covalent Inhibitors for Drug Design

3. Zielgerichtete kovalente Inhibitoren für das Wirkstoffdesign

4. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

5. Covalent binders in drug discovery

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