Fragment‐Based Nuclear Magnetic Resonance Screen against a Regulator of G Protein Signaling Identifies a Binding “Hot Spot”

Author:

Hayes Michael P.12,O'Brien Joseph B.1,Crawford Rachel A.1,Fowler C. Andrew34,Yu Liping3,Doorn Jonathan A.15,Roman David L.15

Affiliation:

1. Department of Pharmaceutical Sciences and Experimental Therapeutics College of Pharmacy University of Iowa 180 S Grand Avenue, CPB 538 Iowa City IA 52245 USA

2. Present address: Beckman Coulter Indianapolis IN 46268 USA

3. NMR Facility, Roy J. and Lucille A. Carver College of Medicine University of Iowa 285 Newton Rd Iowa City IA 52245 USA

4. Present address: Bruker Biospin Corporation Billerica MA 01821–3991 USA

5. Iowa Neuroscience Institute Roy J. and Lucille A. Carver College of Medicine University of Iowa Iowa City IA 52242 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The roles of RGS proteins in cardiometabolic disease;British Journal of Pharmacology;2023-04-19

2. Fragment-to-Lead Medicinal Chemistry Publications in 2021;Journal of Medicinal Chemistry;2023-01-09

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