Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: “Accelerated aging” or a prelude to Alzheimer's disease?

Author:

Rosas H. Diana12,Lewis Lydia R.12,Mercaldo Nathaniel D.1,Nasr Shahin2,Brickman Adam M.345,Siless Viviana2,Yassa Michael6,Sathishkumar Mithra6,Lott Ira78,Schupf Nicole3495,Silverman Wayne8,Lai Florence1,

Affiliation:

1. Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA

2. Department of Radiology Athinoula Martinos Center Massachusetts General Hospital Harvard Medical School Charlestown Massachusetts USA

3. G. H. Sergievsky Center and Taub Institute for Research on Alzheimer's Disease and the Aging Brain College of Physicians and Surgeons Columbia University New York USA

4. Department of Neurology Columbia University New York USA

5. Department of Epidemiology Mailman School of Public Health Columbia University New York USA

6. Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior University of California Irvine California USA

7. Department of Neurology University of California Irvine California USA

8. Department of Pediatrics Irvine Medical Center University of California Irvine California USA

9. Department of Neurology College of Physicians and Surgeons Columbia University New York USA

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

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