Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling
Author:
Affiliation:
1. Clinical Pharmacology, Modeling and Simulation; Amgen, Inc.; South San Francisco CA USA
2. Pharmacokinetics and Drug Metabolism; Amgen, Inc.; Thousand Oaks CA USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.585/fullpdf
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2. Developmental pharmacology-drug disposition, action, and therapy in infants and children;Kearns;N Engl J Med,2003
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4. Physiologically based pharmacokinetic (PBPK) modeling in children;Barrett;Clin Pharmacol Ther,2012
5. Predicting in vivo drug interactions from in vitro drug discovery data;Wienkers;Nature reviews. Drug Discov,2005
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