Low mortality rate in a large cohort of myelin oligodendrocyte glycoprotein antibody disease (<scp>MOGAD</scp>)-Reference-Cited by-同舟云学术

Low mortality rate in a large cohort of myelin oligodendrocyte glycoprotein antibody disease (MOGAD)

Published:2023-02-28 Issue:4 Volume:10 Page:664-667
ISSN:2328-9503
Container-title:Annals of Clinical and Translational Neurology
language:en
Short-container-title:Ann Clin Transl Neurol

Author:

Lotan Itay¹^ORCID,Romanow Gabriela¹,Salky Rebecca¹,Molazadeh Negar¹,Vishnevetsky Anastasia¹,Anderson Monique¹,Bilodeau Philippe Antoine¹,Cutter Gary²,Levy Michael¹^ORCID

Affiliation:

1. Neuroimmunology Clinic and Research Laboratory, Department of Neurology Massachusetts General Hospital, Harvard Medical School Boston Massachusetts USA

2. University of Alabama School of Public Health Birmingham Alabama USA

Abstract

AbstractThe mortality rates of individuals with myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are currently unknown. This study aimed to assess the mortality rate in a large cohort of patients with MOGAD. Since none of the patients in our cohort died, we estimated the upper limit of a 95% confidence interval of the crude mortality rate in the cohort to be 2.1%. These data suggest that mortality in MOGAD is lower than that reported in other neuroinflammatory diseases and comparable to the age‐adjusted mortality rates of the general population in the United States. Additional studies are warranted to confirm this observation.

Publisher

Wiley

Subject

Neurology (clinical),General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/acn3.51750

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