Application of Biaryl Phosphacycles in Palladium‐Catalysed Suzuki‐Miyaura Cross‐Coupling Reactions of Aryl Chlorides

Author:

Lamola Jairus L.1ORCID,Moshapo Paseka T.1,Holzapfel Cedric W.1,Maumela Munaka Christopher12ORCID

Affiliation:

1. Research Centre for Synthesis and Catalysis Chemical Sciences Department University of Johannesburg Kingsway Campus 2006 Auckland Park South Africa

2. Sasol (Pty) Ltd Research & Technology (R & T) 1 Klasie Havenga Rd 1947 Sasolburg South Africa

Abstract

AbstractThe use of Pd‐catalysts based on biaryl phosphacycles allowed facile Suzuki‐Miyaura couplings of a wide range of deactivated, sterically hindered, and heteroaryl chloride substrates with aryl boronic acids. Notably, the strongly electron‐deficient and sufficiently hindered biaryl phosphacycle ligand 7 consistently demonstrated effective performance.

Publisher

Wiley

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