Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution

Author:

Elsner Felix123,Hoffmann Martin4,Fahrioglu‐Yamaci Rezan1,Czyz Zbigniew1,Feliciello Giancarlo4,Mederer Tobias1ORCID,Polzer Bernhard4,Treitschke Steffi4,Rümmele Petra23,Weber Florian2,Wiesinger Hellmuth5,Robold Tobias6,Sziklavari Zsolt78,Sienel Wulf9,Hofmann Hans‐Stefan67,Klein Christoph A14ORCID

Affiliation:

1. Experimental Medicine and Therapy Research University of Regensburg Regensburg Germany

2. Institute of Pathology University of Regensburg Regensburg Germany

3. Institute of Pathology University Hospital Erlangen Erlangen Germany

4. Division of Personalized Tumour Therapy Fraunhofer ITEM‐R Regensburg Germany

5. Gemeinschaftspraxis für Pathologie Regensburg Regensburg Germany

6. Department of Thoracic Surgery University Hospital Regensburg Regensburg Germany

7. Department of Thoracic Surgery Krankenhaus Barmherzige Brüder Regensburg Regensburg Germany

8. Department of Thoracic Surgery Klinikum Coburg Coburg Germany

9. Department of Thoracic Surgery University of Munich Munich Germany

Funder

Deutsche Krebshilfe

European Research Council

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference60 articles.

1. The biology and management of non-small cell lung cancer

2. SEER*Explorer National Cancer Institute.2021; Accessed 25 April 2022] Available from:https://seer.cancer.gov/statistics‐network/explorer/application.html?site=47&data_type=4&graph_type=5&compareBy=sex&chk_sex_1=1&chk_sex_3=3&chk_sex_2=2&series=9&race=1&age_range=1&stage=101&advopt_precision=1&advopt_show_ci=on

3. The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer

4. Emerging Biological Principles of Metastasis

5. Immunohistochemical assessment of individual tumor cells in lymph nodes of patients with non-small-cell lung cancer.

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