Sexual Health Assessment in Women with Lung Cancer study: Sexual health assessment in women with lung cancer

Author:

Florez Narjust12ORCID,Kiel Lauren2,Meza Kelly2,Wei Zihan2,Mazzola Emanuele2,Velazquez Ana I.3ORCID,Franco Idalid124,Fidler Mary Jo5,Elkins Ivy6,Feldman Jill6ORCID,Seaborne Lori7,Heisler Christine7ORCID,King Jennifer C.8ORCID,Moore Amy9,Wiens Jacinta10,Kushner David7

Affiliation:

1. Harvard Medical School Boston Massachusetts USA

2. Dana‐Farber Cancer Institute Boston Massachusetts USA

3. UCSF Helen Diller Family Comprehensive Cancer Center University of California San Francisco San Francisco California USA

4. Brigham and Women’s Hospital Boston Massachusetts USA

5. Rush University Medical Center Chicago Illinois USA

6. EGFR Resisters Chicago Illinois USA

7. University of Wisconsin Madison Wisconsin USA

8. GO2 for Lung Cancer Washington District of Columbia USA

9. LUNGevity Foundation for Lung Cancer Bethesda Maryland USA

10. Merck Pharmaceuticals Rahway New Jersey USA

Abstract

AbstractBackgroundSexual health is understudied and underreported in patients with lung cancer, and most data precede the approval of widely used targeted therapies and immune checkpoint inhibitors. The authors sought to evaluate the prevalence of sexual dysfunction in women with lung cancer in our current clinical environment.MethodsThis cross‐sectional survey study was administered online to 249 women via the GO2 for Lung Cancer (GO2) Registry, using the Patient‐Reported Outcomes Measurement Information System Sexual Function and Satisfaction Measures questionnaire. Participants were recruited between June 2020 to June 2021. Eligibility criteria included age >18 years, self‐identifying as a woman, fluency in English, and a lung cancer diagnosis within 10 years.ResultsMost (67%) had stage IV lung cancer and 47% were receiving targeted therapy; 66% were undergoing active treatment. Despite 54% of participants reporting “recent” sexual activity, most (77%) indicated having little to no interest in sexual activity and 48% reported recent minimal satisfaction with their sex life. The most common reasons negatively affecting participants' satisfaction with their sex life included fatigue (40%) and feeling sad/unhappy (28%). Common reasons for lack of recent sexual activity included lack of interest (68%) and vaginal dryness or pain (30%). Compared to pre‐diagnosis, women were significantly less likely to have recent interest in sexual activity. In multivariable logistic‐regression, vaginal dryness showed a significant negative association with recent interest in sexual activity.ConclusionsSexual dysfunction is prevalent in women with lung cancer. Sexual health should be integrated into routine care for patients with lung cancer.

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference54 articles.

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4. Sexuality in older adults: behaviours and preferences

5. Mayo Clinic.Female sexual dysfunction.2022. Retrieved on 2023 Accessed September 19 2023.https://www.mayoclinic.org/diseases‐conditions/female‐sexual‐dysfunction/symptoms‐causes/syc‐20372549

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