GPS for QSP: A Summary of the ACoP6 Symposium on Quantitative Systems Pharmacology and a Stage for Near‐Term Efforts in the Field

Author:

Musante CJ1,Abernethy DR2,Allerheiligen SR3,Lauffenburger DA4,Zager MG5

Affiliation:

1. Cardiovascular and Metabolic Diseases Research Unit, Pfizer Inc. Cambridge Massachusetts USA

2. Office of Clinical Pharmacology, Office of Translational Sciences Center for Drug Evaluation and Research, U.S. Food and Drug Administration Silver Spring Maryland USA

3. Quantitative Pharmacology and Pharmacometrics Merck Research Labs, Merck & Co Rahway New Jersey USA

4. Massachusetts Institute of Technology Cambridge Massachusetts USA

5. Quantitative Sciences Janssen Research and Development San Diego California USA

Abstract

Quantitative Systems Pharmacology (QSP) is experiencing increased application in the drug discovery and development process. Like its older sibling, systems biology, the QSP field is comprised of a mix of established disciplines and methods, from molecular biology to engineering to pharmacometrics. As a result, there exist critical segments of the discipline that differ dramatically in approach and a need to bring these groups together toward a common goal.

Publisher

Wiley

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