Affiliation:
1. Laboratorio de Polímeros, Instituto de Ciencias Básicas e Ingeniería Universidad Autónoma del Estado de Hidalgo Pachuca Hidalgo Mexico
2. Área Académica de Odontología, Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo Pachuca Hidalgo Mexico
Abstract
AbstractThe aim of this study is to synthesize two eugenol‐derived halogenated monomers and to evaluate their properties as antibacterial and antifungal agents in the formulation of dental composite resins. The 4‐allyl‐2‐methoxyphenyl (2‐chloroethyl) carbonate (ECl) and 4‐allyl‐2‐methoxyphenyl 2,2,3,3,4,4,4‐heptafluorobutanoate (EF) monomers have halogens, chlorine or fluorine bonded in their structure, whose antibacterial activity is known. The characterization of ECl and EF monomers was made by Fourier transform infrared and 1H and 13C NMR. dental resin composites are formulated by mixing the BisGMA/TEGDMA, photoinitiator system, inorganic filler, and the ECl or EF monomer, respectively. The antimicrobial and antifungal activity of the experimental resins is determined using the strains of Staphylococcus aureus and Candida albicans. After copolymerization, DCRs with ECl or EF monomers significantly stop antibacterial growth and show excellent antifungal effect. The best results in the antibacterial test are using 0.5 or 3 wt% of the ECl monomer, while for the EF monomer is 5 wt%. On the other hand, the most adequate concentration of ECl and EF monomers in the antifungal activity is 0.5 wt%. The above demonstrates the ability of ECl and EF monomers to prevent antibacterial and antifungal growth in a dental composite resin, which would extend the useful life of a dental restoration.
Subject
Materials Chemistry,Polymers and Plastics,Surfaces, Coatings and Films,General Chemistry