Narcolepsy following COVID‐19: A case report and review of potential mechanisms

Author:

Roya Yazdani1,Farzaneh Barzkar2ORCID,Mostafa Almasi‐Dooghaee1,Mahsa Shojaie1,Babak Zamani1

Affiliation:

1. Firoozgar Hospital, Department of Neurology, School of Medicine Iran University of Medical Sciences Tehran Iran

2. Center for Educational Research in Medical Sciences(CERMS), Faculty of Medicine Iran University of Medical Sciences IUMS Tehran Iran

Abstract

Key Clinical MessageThe immune activation in COVID‐19 may trigger narcolepsy in vulnerable patients. We suggest clinicians carefully evaluate patients with post‐COVID fatigue and hypersomnia for primary sleep disorders, specifically narcolepsy.AbstractThe patient is a 33‐year‐old Iranian woman without a significant past medical history with the full range of narcolepsy symptoms that started within 2 weeks after her recovery from COVID‐19. Sleep studies revealed increased sleep latency and three sleep‐onset rapid eye movement events, compatible with a narcolepsy‐cataplexy diagnosis.

Publisher

Wiley

Subject

General Medicine

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4. The international classification of sleep disorders, third edition. American Academy of sleep Medicine. Includes bibliographies and index;Ito E;Nihon Rinsho,2015

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