Supramolecular Nanosubstrate‐Mediated Delivery for CRISPR/Cas9 Gene Disruption and Deletion

Author:

Ban Qian1,Yang Peng2,Chou Shih‐Jie3,Qiao Li1,Xia Haidong1,Xue Jingjing2,Wang Fang4,Xu Xiaobin56,Sun Na2,Zhang Ryan Y.2,Zhang Ceng2,Lee Athena2,Liu Wenfei5,Lin Ting‐Yi3,Ko Yu‐Ling3,Antovski Petar2,Zhang Xinyue2,Chiou Shih‐Hwa3,Lee Chin‐Fa7,Hui Wenqiao8,Liu Dahai9,Jonas Steven J.10,Weiss Paul S.5,Tseng Hsian‐Rong2ORCID

Affiliation:

1. School of Life Sciences Center for Stem Cell and Translational Medicine Anhui University Hefei 230601 China

2. Department of Molecular and Medical Pharmacology David Geffen School of Medicine California NanoSystems Institute (CNSI) Crump Institute for Molecular Imaging (CIMI) University of California, Los Angeles Los Angeles CA 90095 USA

3. Department of Medical Research and Stem Cell Center Division of Basic Research Taipei Veterans General Hospital Institute of Pharmacology College of Medicine National Yang Ming Chiao Tung University No. 155, Sec. 2, Linong Street 112 Taipei Taiwan

4. Department of Macromolecular Science State Key Laboratory of Molecular Engineering of Polymers Fudan University Shanghai 200433 China

5. Department of Chemistry and Biochemistry Department of Bioengineering Department of Materials Science and Engineering California NanoSystems Institute (CNSI) University of California, Los Angeles Los Angeles CA 90095 USA

6. School of Materials Science and Engineering Tongji University 1239 Siping Road Shanghai 200092 China

7. Department of Chemistry i‐Center for Advanced Science and Technology (iCAST) Innovation and Development Center of Sustainable Agriculture National Chung Hsing University (NCHU) 145 Xingda Road, South Dist. Taichung 402 Taiwan

8. Anhui Province Key Laboratory of Livestock and Poultry Product Safety Engineering Institute of Animal Husbandry and Veterinary Medicine Anhui Academy of Agriculture Sciences Hefei 230031 China

9. School of Stomatology and Medicine Foshan University Foshan 528000 China

10. Department of Pediatrics David Geffen School of Medicine California NanoSystems Institute (CNSI) Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research Children's Discovery and Innovation Institute University of California, Los Angeles Los Angeles CA 90095 USA

Funder

National Institutes of Health

National Institute of Dental and Craniofacial Research

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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