Natural Extracts for Antibacterial Applications

Author:

Chen Cuihong123,Chen Lin123,Mao Congyang1,Jin Liguo134,Wu Shuilin134ORCID,Zheng Yufeng3,Cui Zhenduo4,Li Zhaoyang4,Zhang Yu5,Zhu Shengli4,Jiang Hui4,Liu Xiangmei12

Affiliation:

1. Biomedical Materials Engineering Research Center Hubei Key Laboratory of Polymer Materials Ministry‐of‐Education Key Laboratory for the Green Preparation and Application of Functional Materials School of Materials Science & Engineering State Key Laboratory of Biocatalysis and Enzyme Engineering Hubei University Wuhan 430062 China

2. School of Health Science & Biomedical Engineering Hebei University of Technology Xiping Avenue 5340# Tianjin 300401 China

3. School of Materials Science & Engineering Peking University Yiheyuan Road 5# Beijing 100871 China

4. School of Materials Science & Engineering the Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China Tianjin University Yaguan Road 135# Tianjin 300072 China

5. Department of Orthopedics Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou 510080 China

Abstract

AbstractBacteria‐induced epidemics and infectious diseases are seriously threatening the health of people around the world. In addition, antibiotic therapy has been inducing increasingly more serious bacterial resistance, which makes it urgent to develop new treatment strategies to combat bacteria, including multidrug‐resistant bacteria. Natural extracts displaying antibacterial activity and good biocompatibility have attracted much attention due to greater concerns about the safety of synthetic chemicals and emerging drug resistance. These antibacterial components can be isolated and utilized as antimicrobials, as well as transformed, combined, or wrapped with other substances by using modern assistive technologies to fight bacteria synergistically. This review summarizes recent advances in natural extracts from three kinds of sources—plants, animals, and microorganisms—for antibacterial applications. This work discusses the corresponding antibacterial mechanisms and the future development of natural extracts in antibacterial fields.

Funder

National Natural Science Foundation of China

China National Funds for Distinguished Young Scientists

Natural Science Foundation of Beijing Municipality

Hubei Provincial Central Guidance Local Science and Technology Development Project

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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