Metopimazine is primarily metabolized by a liver amidase in humans

Author:

Busby Robert W.1ORCID,Cai Xiaokun2,Yang Sihyung2,Ramos Luis2,Venkatarangan Lata2,Shen Helen2,Wax Stephen1,Sadeque Abu J. M.2,De Colle Cyril1

Affiliation:

1. Neurogastrx, Inc. Woburn Massachusetts USA

2. QPS Newark Delaware USA

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference32 articles.

1. Clinical guideline: management of gastroparesis;Camilleri M;Am J Gastroenterol,2013

2. 1079 NG101: a potent and selective dopamine D2 receptor antagonist as a potential alternative to metoclopramide and domperidone for the treatment of gastroparesis;De Colle C;Gastroenterology,2016

3. Gastroparesis a review of current diagnosis and treatment options;Stein B;J Clin Gastroenterol,2015

4. The effect of food on serum concentrations of metopimazine;Herrstedt J;Br J Clin Pharmacol,1990

5. Pharmacokinetic study of metopimazine by oral route in children;Mallet E;Pharmacol Res Perpect,2015

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