Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

Author:

Carapuça Elisabete F1,Gemenetzidis Emilios1,Feig Christine2,Bapiro Tashinga E2,Williams Michael D2,Wilson Abigail S1,Delvecchio Francesca R1,Arumugam Prabhu1,Grose Richard P1,Lemoine Nicholas R3,Richards Frances M2,Kocher Hemant M14ORCID

Affiliation:

1. Centre for Tumour Biology, Barts Cancer Institute; Queen Mary University of London; London UK

2. The University of Cambridge Cancer Research-UK Cambridge Institute; Li Ka Shing Centre, Robinson Way Cambridge UK

3. Centre for Molecular Oncology; Barts Cancer Institute, Queen Mary University of London; London UK

4. Barts and The London HPB Centre; The Royal London Hospital; Barts Health NHS Trust London UK

Funder

Knowledge Transfer Network (Engineering and Physical Sciences Research Committee) and Pancreatic Cancer Research Fund (UK)

EMBO Long-Term Fellowship

Marie Curie Intra-European Fellowship within the 7th European Community Framework Programme

Cancer Research UK

Pancreatic Cancer Research Fund

Barts Charity

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference41 articles.

1. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer;Conroy;N Engl J Med,2011

2. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine;Von Hoff;N Engl J Med,2013

3. National Institute for Health and Care Excellence 2001 https://www.nice.org.uk/guidance/ta25

4. Stromal biology and therapy in pancreatic cancer: a changing paradigm;Neesse;Gut,2015

5. Stromal biology and therapy in pancreatic cancer;Neesse;Gut,2011

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