Breast cancer diagnosis and management guided by data augmentation, utilizing an integrated framework of SHAP and random augmentation

Author:

Ejiyi Chukwuebuka Joseph1ORCID,Qin Zhen1,Monday Happy2,Ejiyi Makuachukwu Bennedith3,Ukwuoma Chiagoziem1,Ejiyi Thomas Ugochukwu4,Agbesi Victor Kwaku5,Agu Amarachi6,Orakwue Chiduzie7

Affiliation:

1. School of Information and Software Engineering, University of Electronic Science and Technology of China Chengdu China

2. Department of Computer Science Oxford Brookes University and Chengdu University of Technology of China Chengdu China

3. Department of Pharmacy University of Nigeria Nsukka Enugu Nigeria

4. Department of Pure and Industrial Chemistry University of Nigeria Nsukka Enugu Nigeria

5. School of Computer Science and Engineering, University of Electronic Science and Technology of China Chengdu China

6. Department of Public Health University of Nigeria Enugu Campus Enugu Nigeria

7. Department of Agricultural and Bio‐Resources Engineering College of Engineering Federal University of Agriculture Abeokuta Nigeria

Abstract

AbstractRecent research indicates that early detection of breast cancer (BC) is critical in achieving favorable treatment outcomes and reducing the mortality rate associated with it. With the difficulty in obtaining a balanced dataset that is primarily sourced for the diagnosis of the disease, many researchers have relied on data augmentation techniques, thereby having varying datasets with varying quality and results. The dataset we focused on in this study is crafted from SHapley Additive exPlanations (SHAP)‐augmentation and random augmentation (RA) approaches to dealing with imbalanced data. This was carried out on the Wisconsin BC dataset and the effectiveness of this approach to the diagnosis of BC was checked using six machine‐learning algorithms. RA synthetically generated some parts of the dataset while SHAP helped in assessing the quality of the attributes, which were selected and used for the training of the models. The result from our analysis shows that the performance of the models used generally increased to more than 3% for most of the models using the dataset obtained by the integration of SHAP and RA. Additionally, after diagnosis, it is important to focus on providing quality care to ensure the best possible outcomes for patients. The need for proper management of the disease state is crucial so as to reduce the recurrence of the disease and other associated complications. Thus the interpretability provided by SHAP enlightens the management strategies in this study focusing on the quality of care given to the patient and how timely the care is.

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Molecular Medicine,General Medicine,Biochemistry

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