Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors-Reference-Cited by-同舟云学术

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Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors

Published:2015-12-20 Issue:2 Volume:349 Page:104-111
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Abdel-Rahman Hamdy M.¹,Abdel-Aziz Mohamed²,Tinsley Heather N.³,Gary Bernard D.⁴,Canzoneri Joshua C.⁴,Piazza Gary A.⁴

Affiliation:

1. Department of Medicinal Chemistry, Faculty of Pharmacy; Assiut University; Assiut Egypt

2. Department of Medicinal Chemistry, Faculty of Pharmacy; Minia University; Minia Egypt

3. Department of Biology, Chemistry and Mathematics; University of Montevallo; Montevallo AL USA

4. Mitchell Cancer Institute; University of South Alabama; Mobile AL USA

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201500363/fullpdf

Reference24 articles.

1. Recent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease

2. 2 PDE4 Inhibitors – A Review of the Current Field

3. Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode

4. Pyrazolopyridines as potent PDE4B inhibitors: 5-Heterocycle SAR

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1. Synthesis and Characterization of New N-acyl Hydrazone Derivatives of Carprofen as Potential Tuberculostatic Agents;Antibiotics;2024-02-23

2. Advances in the development of phosphodiesterase-4 inhibitors;European Journal of Medicinal Chemistry;2023-03

3. Portraying molecular modulation and therapeutic aspects of psoriasis: Retrospection and current status;Journal of Molecular Structure;2021-11

4. Synthesis, Characterization and computational study of N-Acylhydrazone derivatives.;Egyptian Journal of Chemistry;2021-04-29

5. Quinazolinone-Schiff's Base hybrids as Phosphodiesterase 4B inhibitors with dual activity against COPD and Lung Cancer;Egyptian Journal of Chemistry;2020-06-06

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