Crude extract ofRheum palmatum Linhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling

Author:

Ma Yi-Shih123,Hsiao Yu-Ping45,Lin Ju-Hwa6,Hsu Shu-Chun6,Chueh Fu-Shin7,Weng Shu-Wen189,Lai Kuang-Chi1011,Lin Jaung-Geng1,Chung Jing-Gung612

Affiliation:

1. Graduate Institute of Chinese Medicine; China Medical University; No 91, Hsueh-Shih Road Taichung 402 Taiwan Republic of China

2. Department of Chinese Medicine; Changhua Hospital; Changhua Taiwan Republic of China

3. Department of Health; Executive Yuan; Changhua Taiwan Republic of China

4. Departments of Dermatology; Chung Shan Medical University Hospital; Taichung 402 Taiwan Republic of China

5. Institute of Medicine; Chung Shan Medical University; Taichung 402 Taiwan Republic of China

6. Departments of Biological Science and Technology; China Medical University; No 91, Hsueh-Shih Road Taichung 402 Taiwan Republic of China

7. Department of Health and Nutrition Biotechnology; Asia University; Taichung 413 Taiwan Republic of China

8. Department of Chinese Medicine; Taichung Hospital; Taichung 403 Taiwan Republic of China

9. Department of Health; Executive Yuan; Taichung 403 Taiwan Republic of China

10. School of Medicine, China Medical University; No 91, Hsueh-Shih Road Taichung 402 Taiwan Republic of China

11. Department of Surgery; China Medical University Beigang Hospital; Yunlin 651 Taiwan Republic of China

12. Department of Biotechnology; Asia University; Taichung 413 Taiwan Republic of China

Funder

China Medical University

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Reference45 articles.

1. Matrix metalloproteinases: Potential therapy to prevent the development of second malignancies after breast radiotherapy;Artacho-Cordon;Surg Oncol,2012

2. Cetuximab in metastatic colorectal cancer;Broadbridge;Expert Rev Anticancer Ther,2012

3. Antiproliferative activity of Chinese medicinal herbs on breast cancer cells in vitro;Campbell;Anticancer Res,2002

4. The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino) quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor;Chen;Int J Oncol,2011

5. The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients;Chen;Genet Test Mol Biomarkers,2009

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