Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

Author:

Liu Qi1,Zhao Kai2,Wang Chun1,Zhang Zhanzhan1,Zheng Chunxiong1,Zhao Yu1,Zheng Yadan1,Liu Chaoyong2,An Yingli1,Shi Linqi1,Kang Chunsheng2,Liu Yang1ORCID

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology; Key Laboratory of Functional Polymer Materials of Ministry of Education; College of Chemistry; Nankai University; Tianjin 300071 China

2. Tianjin Neurological Institute; Key Laboratory of Post-neurotrauma Neuro-repair and Regeneration in Central Nervous System; Ministry of Education and Tianjin City; Department of Neurosurgery; Tianjin Medical University General Hospital; Tianjin 300052 China

Funder

National Key Research and Development Programs of China

National Natural Science Foundation of China

PCSIRT

Thousand Talents Program for Young Professionals

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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