The bacterial pathogen Pseudomonas plecoglossicida, its epidemiology, virulence factors, vaccine development, and host–pathogen interactions

Author:

Mao Zhijuan1,Li Shanshan1,Li Yiying1,Jia Tingting1

Affiliation:

1. Biological and Environmental College Zhejiang Wanli University Ningbo China

Abstract

AbstractObjectivePseudomoans plecoglossicida has been identified as a fish pathogen since 2000 and has caused serious infections in cultured Large Yellow Croakers Larimiththys crocea in coastal eastern China during recent years.MethodsPublished literatures of this pathogen have been reviewed.ResultSeveral strains with high genomic similarity have been isolated and identified; the bacteria induce natural infection at lower water temperatures (12.0–25.5°C) and induce numerous granulomas and nodules in the visceral organs of croakers. Researchers have investigated the epidemiology of P. plecoglossicida infection, identified major virulence factors, searched for pathogenic genes, analyzed host‐pathogen interactions, and endeavored to develop efficient vaccines.ConclusionThis paper provides an overview of these research advances to elucidate the virulence mechanisms of the pathogen and to promote vaccine development against infection.

Publisher

Wiley

Reference56 articles.

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