Affiliation:
1. Department of Plastic and Aesthetic Surgery, Hand Surgery Helios Hospital Emil von Behring Berlin Germany
2. Department of Pathology Helios Hospital Emil von Behring Berlin Germany
3. Department of Dermatology University Hospital Regensburg Germany
4. Department of Radiotherapy Helios Hospital Emil von Behring Berlin Germany
Abstract
Key Clinical MessageEarly and complete surgical resection is the most important therapeutic and diagnostic measure. Adjuvant radiation is suggested for malign phyllode tumors, phyllode tumors larger than 10 cm or those with a low distance to the resection margins.AbstractPhyllodes tumors are rare fibroepithelial tumors of the breast. Histologically, they are usually classified as benign, borderline or malignant, though these classifications do not necessarily reflect the clinical course of the disease. These tumors may stay undetected for years, or show sudden and rapid progression. There is currently no consistent therapy recommendation based upon histological findings, the localization of the tumor and/or whether it is recurrent. Using the examples of three patients, we show how courses and therapy may differ widely, and discuss this in the context of the current state of the literature.