Affiliation:
1. Department of Health Assistant Shiraz University of Medical Sciences Shiraz Iran
2. Department of Midwifery Qom University of Medical Sciences Qom Iran
3. Midwifery Department Ministry of Health and Medical Education Tehran Iran
4. Department of Epidemiology and Biostatistics Birjand University of Medical Sciences Birjand Iran
5. Department of Gynecology and Obstetrics University Hospitals Schleswig‐Holstein, Campus Kiel Kiel Germany
Abstract
AbstractBackground and AimEndometrial cancer (EC) is the sixth most common cancer among women worldwide. Since global studies are based on awareness of the incidence trend, mortality, geographical diversity, and level of social development and income of countries, this study was conducted to investigate the trend of uterine cancer (UC) in the world in 2019.MethodsAge‐standardized rates (ASR) of incidence, deaths, prevalence, and disability‐adjusted life years (DALYs) of UC, as well as targeted risk factors, were extracted from the Global Burden of Disease (GBD) online database 2019. Pearson correlation coefficient and SPSS 16 were used to calculate the correlation between risk factors and ASR of epidemiological indicators. Statistical significance was considered as p < 0.05.ResultsIn 2019, the age‐specific incidence and death rate of UC was peaking at 60–64 and 65–69 years, respectively. The highest age‐standardized incidence rate per 100,000 people for UC has been reported in the Northern Mariana Islands, high sociodemographic index (SDI) countries, World Bank High‐Income category, Europe continent and among World Health Organization (WHO) regions were found in the European Region. The highest age‐standardized death rate per 100,000 people for UC has been reported in Grenada, high SDI countries, the World Bank High‐Income category, Europe continent, and among WHO regions found in the European Region. In 2019, the age‐standardized DALYs rate was 53.54 per 100,000 inhabitants, of which 48.49 cases were related to years of life lost (YLLs) and 5.05 cases were related to years lived with disability.ConclusionAccording to GBD‐2019, the highest incidence, mortality, and DALY of UC are in Europe. The evidence and traces of diversity can be seen in the inequalities of UC. Race, ethnicity, economic status, level of education and awareness, co‐morbidities, access, grade, and histological type of tumor are the most important causes of this inequality.