Comparative pharmacokinetics of prim-O-glucosylcimifugin and cimifugin by liquid chromatography-mass spectrometry after oral administration of Radix Saposhnikoviae extract, cimifugin monomer solution and prim-O-glucosylcimifugin monomer solution to rats

Author:

Li Yueyue1,Zhao Liang,Zhang Hai1,Jia Jing1,Lv Lei1,Zhou Guichen1,Chai Yifeng2,Zhang Guoqing1

Affiliation:

1. Department of Pharmacy, Eastern Hepatobiliary Surgery Hospital; Second Military Medical University; Shanghai; 200438; China

2. School of Pharmacy; Second Military Medical University; No. 325, Guohe Road; Shanghai; 200433; China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference15 articles.

1. A sensitive liquid chromatography-mass spectrometry method for simultaneous determination of two active chromones from Saposhnikovia root in rat plasma and urine;Dai;Journal of Chromatography B,2008

2. Isolation and structure identification of chemical constituents from Saposhnikovia divaricata (Turcz.) Schischk;Jiang;Acta Pharmaceutica Sinica,2007

3. Characterization of compounds from the roots of Saposhnikovia divaricata by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry;Kang;Rapid Communications in Mass Spectrometry,2008

4. Determination of four components in root of Saposhnikovia divaricata by HPLC gradient elution;Li;Zhongguo Zhong Yao Za Zhi,2006a

5. Experimental Study of Pharmacological Action of Active Composition of Radix Saposhnikoviae;Li;Zhongguo Shi Yan Fang Ji Xue Za Zhi,2006b

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