Intracellular metabolic flux analysis of CHO cells supplemented with wheat hydrolysates for improved mAb production and cell-growth-Reference-Cited by-同舟云学术

Intracellular metabolic flux analysis of CHO cells supplemented with wheat hydrolysates for improved mAb production and cell-growth

Published:2014-09-29 Issue:2 Volume:90 Page:291-302
ISSN:0268-2575
Container-title:Journal of Chemical Technology & Biotechnology
language:en
Short-container-title:J. Chem. Technol. Biotechnol.

Author:

Lee Hae Woo¹,Christie Andrew²,Starkey Jason A.³,Read Erik K.⁴,Yoon Seongkyu⁵

Affiliation:

1. Clinical Manufacturing Center; Daegu-Gyeongbuk Medical Innovation Foundation; Cheombok-ro 80, Dong-gu, Daegu South Korea

2. SAFC Biosciences; Lenexa KS USA

3. Pfizer Inc; Chesterfield MO USA

4. Divison of Monoclonal Antibodies; OBP/OPS/CDER/FDA; Silver Spring MD

5. Department of Chemical Engineering; University of Massachusetts; Lowell MA USA

Funder

Massachusetts Life Science Center

Pfizer

University of Massachusetts Lowell

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology

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4. Recombinant protein expression for therapeutic applications;Andersen;Curr Opin Biotechnol,2002

5. Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor;Ozturk;Biotechnol Bioeng,1997

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