Characterization of chromosome 11 breakpoints and the areas of deletion and amplification in patients with newly diagnosed acute myeloid leukemia

Author:

Sarova Iveta12,Brezinova Jana1,Zemanova Zuzana2,Bystricka Dagmar2,Krejcik Zdenek1,Soukup Petr1,Vydra Jan1,Cermak Jaroslav1,Jonasova Anna3,Michalova Kyra12

Affiliation:

1. Cytogenetic Department; Institute of Hematology and Blood Transfusion; Prague Czech Republic

2. Center of Oncocytogenetics; Institute of Medical Biochemistry and Laboratory Diagnostics; General Faculty Hospital and 1 Faculty of Medicine of Charles University; Prague Czech Republic

3. 1 Faculty of Medicine; Charles University in Prague; Czech Republic

Funder

MHCR for conceptual development of research organization

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference33 articles.

1. The MLL gene and translocations involving chromosomal band 11q23 in acute leukemia;Braekeleer;Anticancer Res,2005

2. Cryptic t(5;11)(q35;p15.5) in adult de novo acute myelocytic leukemia with normal karyotype;Casas;Cancer Genet Cytogenet Sep,2003

3. Complex and cryptic chromosomal rearrangements involving the MLL gene in acute leukemia: A study of 7 patients and review of the literature;Braekeleer;Blood Cells Mol Dis,2010

4. Using bacterial artificial chromosomes in leukemia research: The experience at the university cytogenetics laboratory in Brest, France;Braekeleer;J Biomed Biotechnol,2011

5. The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): Analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial;Grimwade;Blood,2001

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