The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone

Author:

Dahan Arik,Miller Jonathan M.,Hoffman Amnon,Amidon Gregory E.,Amidon Gordon L.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference36 articles.

1. Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs;Dahan;J Control Release,2008

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv Drug Deliv Rev,2001

3. Property-based design: Optimization of drug absorption and pharmacokinetics;Van de Waterbeemd;J Med Chem,2001

4. Gastrointestinal dissolution and absorption of class II drugs;Dahan,2008

5. Enhanced gastrointestinal absorption of lipophilic drugs;Dahan,2006

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